Idris: There's a sign on my front door. You've been walking past it for seven hundred years. What does it say?
The Doctor: That's not instructions.
Idris: There's an instruction at the bottom. What does it say?
The Doctor: "Pull to open."
Idris: Yes, and what do you do?
The Doctor: I push!
"I wear a fez now. Fezzes are cool."
less for the line than for the reaction :D
It's epic either way. ^-^
I don't have a specific Doctor Who quote but I always loved the the parts where he has this distant look and his eyes are glazed the mysterious music is played in the background and he starts making a speech about Galifray, or timelords, or the way he is powerful and other races fear him or some other deep and important message regarding time and space. You know these parts ;).
LOVED the Shakespeare quote (academics punching the air) but there are so many moments that just catch the imagination. One of my favorites:
Are all people like this?
So much bigger on the inside.
AND STAY OUT!
- The Eleventh Doctor, not so long after regeneration, in the home of Amelia Pond.
4th Dr.- You're improving?!!
Harry- Am I really?
4th Dr.- Yes! Your mind is beginning to work. It's entirely due to my influence, of course, you must not take any credit.
From the "Ark in Space" episode.